Izolacja ludzkiego genu, który hamuje zakażenie HIV-1 i jest tłumiony przez wirusowe białko Vif. Viruses have developed various non-immune methods to counteract host-mediated mechanisms that confer resistance to an infection. The Vif (virion infectivity issue) proteins are encoded by primate immunodeficiency viruses, most notably human immunodeficiency virus-1 (HIV-1). These proteins are potent regulators of virus… Continue reading
Category: peptide
Komórki dendrytyczne i kontrola odporności
Poprawa czasu przeżycia przy stosowaniu ipilimumabu u pacjentów z przerzutowym czerniakiem BACKGROUND An enchancment in general survival amongst sufferers with metastatic melanoma has been an elusive aim. On this section Three examine, ipilimumab–which blocks cytotoxic T-lymphocyte-associated antigen Four to potentiate an antitumor T-cell response–administered with or with out a glycoprotein 100 (gp100) peptide vaccine was in… Continue reading
cytokiną krytyczną dla autoimmunologicznego zapalenia mózgu
Interleukina-23 zamiast interleukiny-12 jest cytokiną krytyczną dla autoimmunologicznego zapalenia mózgu. Interleukin-12 (IL-12) is a heterodimeric molecule composed of p35 and p40 subunits. Analyses in vitro have outlined IL-12 as an necessary issue for the differentiation of naive T cells into T-helper kind 1 CD4+ lymphocytes secreting interferon-gamma (refs 1, 2). Equally, quite a few research have concluded that IL-12… Continue reading